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KSHV LANA inhibits TGF-β signaling through epigenetic silencing of the TGF-β type II receptor
Signaling through the transforming growth factor–β (TGF-β) pathway results in growth inhibition and induction of apoptosis in various cell types. We show that this pathway is blocked in Kaposi sarcoma herpesvirus (KSHV)–infected primary effusion lymphoma through down-regulation of the TGF-β type II...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society of Hematology
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2343603/ https://ncbi.nlm.nih.gov/pubmed/18199825 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-09-110544 |
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