KSHV LANA inhibits TGF-β signaling through epigenetic silencing of the TGF-β type II receptor

Signaling through the transforming growth factor–β (TGF-β) pathway results in growth inhibition and induction of apoptosis in various cell types. We show that this pathway is blocked in Kaposi sarcoma herpesvirus (KSHV)–infected primary effusion lymphoma through down-regulation of the TGF-β type II...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Di Bartolo, Daniel L., Cannon, Mark, Liu, Yi-Fang, Renne, Rolf, Chadburn, Amy, Boshoff, Chris, Cesarman, Ethel
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society of Hematology 2008
विषय:
Neoplasia
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2343603/
https://ncbi.nlm.nih.gov/pubmed/18199825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-09-110544
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