Paracrine and epigenetic control of CAF-induced metastasis: the role of HOTAIR stimulated by TGF-ß1 secretion

BACKGROUND: The communication between carcinoma associated fibroblasts (CAFs) and cancer cells facilitate tumor metastasis. In this study, we further underlying the epigenetic mechanisms of CAFs feed the cancer cells and the molecular mediators involved in these processes. METHODS: MCF-7 and MDA-MB-...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Ren, Yu, Jia, Huan-huan, Xu, Yi-qi, Zhou, Xuan, Zhao, Xiao-hui, Wang, Yun-fei, Song, Xin, Zhu, Zhi-yan, Sun, Ting, Dou, Yan, Tian, Wei-ping, Zhao, Xiu-lan, Kang, Chun-sheng, Mei, Mei
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5765658/
https://ncbi.nlm.nih.gov/pubmed/29325547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-018-0758-4
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