Blockade of transforming growth factor-β signaling enhances oncolytic herpes simplex virus efficacy in patient-derived recurrent glioblastoma models

Despite the current standard of multimodal management, glioblastoma (GBM) inevitably recurs and effective therapy is not available for recurrent disease. A subset of tumor cells with stem-like properties, termed GBM stem-like cells (GSCs), are considered to play a role in tumor relapse. Although onc...

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Detalhes bibliográficos
Publicado no:Int J Cancer
Main Authors: Esaki, Shinichi, Nigim, Fares, Moon, Esther, Luk, Samantha, Kiyokawa, Juri, Curry, William, Cahill, Daniel P., Chi, Andrew S., Iafrate, A. John, Martuza, Robert L., Rabkin, Samuel D., Wakimoto, Hiroaki
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5765440/
https://ncbi.nlm.nih.gov/pubmed/28801914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.30929
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