A new patient-derived orthotopic malignant meningioma model treated with oncolytic herpes simplex virus

BACKGROUND: Higher-grade meningiomas (HGMs; World Health Organization grades II and III) pose a clinical problem due to high recurrence rates and the absence of effective therapy. Preclinical development of novel therapeutics requires a disease model that recapitulates the genotype and phenotype of...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Nigim, Fares, Esaki, Shin-ichi, Hood, Michael, Lelic, Nina, James, Marianne F., Ramesh, Vijaya, Stemmer-Rachamimov, Anat, Cahill, Daniel P., Brastianos, Priscilla K., Rabkin, Samuel D., Martuza, Robert L., Wakimoto, Hiroaki
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Basic and Translational Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4998993/
https://ncbi.nlm.nih.gov/pubmed/26951380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now031
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