Treatment of orthotopic malignant peripheral nerve sheath tumors with oncolytic herpes simplex virus

BACKGROUNDS: Malignant peripheral nerve sheath tumors (MPNSTs) are an aggressive and often lethal sarcoma that frequently develops in patients with neurofibromatosis type 1 (NF1). We developed new preclinical MPNST models and tested the efficacy of oncolytic herpes simplex viruses (oHSVs), a promisi...

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Detalhes bibliográficos
Main Authors: Antoszczyk, Slawomir, Spyra, Melanie, Mautner, Victor Felix, Kurtz, Andreas, Stemmer-Rachamimov, Anat O., Martuza, Robert L., Rabkin, Samuel D.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096170/
https://ncbi.nlm.nih.gov/pubmed/24470552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/not317
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