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Effect of γ34.5 Deletions on Oncolytic Herpes Simplex Virus Activity in Brain Tumors
The ICP34.5 protein of herpes simplex virus (HSV) is involved in many aspects of viral pathogenesis; promoting neurovirulence, inhibiting interferon-induced shutoff of protein synthesis, interacting with PCNA and TBK1, inhibiting dendritic cell (DC) maturation, and binding to Beclin 1 to interfere w...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3318611/ https://ncbi.nlm.nih.gov/pubmed/22345479 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00017-12 |
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