Safety of single low-dose primaquine in glucose-6-phosphate dehydrogenase deficient falciparum-infected African males: Two open-label, randomized, safety trials

BACKGROUND: Primaquine (PQ) actively clears mature Plasmodium falciparum gametocytes but in glucose-6-phosphate dehydrogenase deficient (G6PDd) individuals can cause hemolysis. We assessed the safety of low-dose PQ in combination with artemether-lumefantrine (AL) or dihydroartemisinin-piperaquine (D...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Bastiaens, Guido J. H., Tiono, Alfred B., Okebe, Joseph, Pett, Helmi E., Coulibaly, Sam A., Gonçalves, Bronner P., Affara, Muna, Ouédraogo, Alphonse, Bougouma, Edith C., Sanou, Guillaume S., Nébié, Issa, Bradley, John, Lanke, Kjerstin H. W., Niemi, Mikko, Sirima, Sodiomon B., d’Alessandro, Umberto, Bousema, Teun, Drakeley, Chris
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2018
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5764271/
https://ncbi.nlm.nih.gov/pubmed/29324864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0190272
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