Safety of single low-dose primaquine in glucose-6-phosphate dehydrogenase deficient falciparum-infected African males: Two open-label, randomized, safety trials

BACKGROUND: Primaquine (PQ) actively clears mature Plasmodium falciparum gametocytes but in glucose-6-phosphate dehydrogenase deficient (G6PDd) individuals can cause hemolysis. We assessed the safety of low-dose PQ in combination with artemether-lumefantrine (AL) or dihydroartemisinin-piperaquine (D...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Bastiaens, Guido J. H., Tiono, Alfred B., Okebe, Joseph, Pett, Helmi E., Coulibaly, Sam A., Gonçalves, Bronner P., Affara, Muna, Ouédraogo, Alphonse, Bougouma, Edith C., Sanou, Guillaume S., Nébié, Issa, Bradley, John, Lanke, Kjerstin H. W., Niemi, Mikko, Sirima, Sodiomon B., d’Alessandro, Umberto, Bousema, Teun, Drakeley, Chris
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2018
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5764271/
https://ncbi.nlm.nih.gov/pubmed/29324864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0190272
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