Enzymes of the one-carbon folate metabolism as anticancer targets predicted by survival rate analysis

The significance of mitochondrial metabolism in cancer cells has recently been gaining attention. Among other findings, One-carbon folate metabolism has been reported to be closely associated with cellular characteristics in cancer. To study molecular targets for efficient cancer therapy, we investi...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Koseki, Jun, Konno, Masamitsu, Asai, Ayumu, Colvin, Hugh, Kawamoto, Koichi, Nishida, Naohiro, Sakai, Daisuke, Kudo, Toshihiro, Satoh, Taroh, Doki, Yuichiro, Mori, Masaki, Ishii, Hideshi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762868/
https://ncbi.nlm.nih.gov/pubmed/29321536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18456-x
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