Mitochondrial pyruvate carrier 1 expression controls cancer epithelial‐mesenchymal transition and radioresistance

Mitochondrial pyruvate carrier (MPC) is known to cause different expressions in normal and cancer cells. We observed a change in phenotype with the suppression of MPC expression. We knocked down MPC1 and/or MPC2 using siRNA or shRNA. We observed its cell morphology and accompanying molecular marker....

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Vydáno v:Cancer Sci
Hlavní autoři: Takaoka, Yuji, Konno, Masamitsu, Koseki, Jun, Colvin, Hugh, Asai, Ayumu, Tamari, Keisuke, Satoh, Taroh, Mori, Masaki, Doki, Yuichiro, Ogawa, Kazuhiko, Ishii, Hideshi
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6447954/
https://ncbi.nlm.nih.gov/pubmed/30801869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13980
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