Cell-free culture conditioned medium elicits pancreatic β cell lineage-specific epigenetic reprogramming in mice

There are several obstacles to overcome prior to achieving cellular reprogramming of pancreatic β cells in vitro and in vivo. The present study demonstrated that the transfer of epigenetic phenotypes was achieved in the cell-free conditioned medium (CM) of pancreatic insulinoma MIN6 cell cultures. T...

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Pubblicato in:Oncol Lett
Autori principali: Kawamoto, Koichi, Ohashi, Tomofumi, Konno, Masamitsu, Nishida, Naohiro, Koseki, Jun, Matsui, Hidetoshi, Sakai, Daisuke, Kudo, Toshihiro, Eguchi, Hidetoshi, Satoh, Taroh, Doki, Yuichiro, Mori, Masaki, Ishii, Hideshi
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2018
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6096232/
https://ncbi.nlm.nih.gov/pubmed/30127922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.9008
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