Simultaneous quantification of DNA damage and mitochondrial copy number by long-run DNA-damage quantification (LORD-Q)

DNA damage and changes in the mitochondrial DNA content have been implicated in ageing and cancer development. To prevent genomic instability and tumorigenesis, cells must maintain the integrity of their nuclear and mitochondrial DNA. Advances in the research of DNA damage protection and genomic sta...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Dannenmann, Benjamin, Lehle, Simon, Lorscheid, Sebastian, Huber, Stephan M., Essmann, Frank, Schulze-Osthoff, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762520/
https://ncbi.nlm.nih.gov/pubmed/29348835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20112
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