Simultaneous quantification of DNA damage and mitochondrial copy number by long-run DNA-damage quantification (LORD-Q)

DNA damage and changes in the mitochondrial DNA content have been implicated in ageing and cancer development. To prevent genomic instability and tumorigenesis, cells must maintain the integrity of their nuclear and mitochondrial DNA. Advances in the research of DNA damage protection and genomic sta...

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Sparad:
Bibliografiska uppgifter
I publikationen:Oncotarget
Huvudupphovsmän: Dannenmann, Benjamin, Lehle, Simon, Lorscheid, Sebastian, Huber, Stephan M., Essmann, Frank, Schulze-Osthoff, Klaus
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2017
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762520/
https://ncbi.nlm.nih.gov/pubmed/29348835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20112
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