Simultaneous Quantification of Mitochondrial DNA Damage and Copy Number in Circulating Blood: A Sensitive Approach to Systemic Oxidative Stress

Systemic oxidative stress is associated with a wide range of pathological conditions. Oxidative DNA damage is frequently measured in circulating lymphocytes. Mitochondrial DNA (mtDNA) is known to be more sensitive to oxidative damage than nuclear DNA but is rarely used for direct measurement of DNA...

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Hlavní autoři: Chan, Sam W., Chevalier, Simone, Aprikian, Armen, Chen, Junjian Z.
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2013
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591215/
https://ncbi.nlm.nih.gov/pubmed/23484085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/157547
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