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Simultaneous quantification of mitochondrial DNA copy number and deletion ratio: A multiplex real-time PCR assay

Mitochondrial dysfunction is implicated in a vast array of diseases and conditions, such as Alzheimer's disease, cancer, and aging. Alterations in mitochondrial DNA (mtDNA) may provide insight into the processes that either initiate or propagate this dysfunction. Here, we describe a unique mult...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Phillips, Nicole R., Sprouse, Marc L., Roby, Rhonda K.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4894387/
https://ncbi.nlm.nih.gov/pubmed/24463429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep03887
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