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Differential quantification of CYP2D6 gene copy number by four different quantitative real-time PCR assays

OBJECTIVE: Copy number variations (CNVs) in the CYP2D6 gene contribute to interindividual variation in drug metabolism. Since the most common duplicated allele in Asian populations is the nonfunctional CYP2D6*36 allele, the goal of this study was to identify CNV assays that can differentiate between...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Pharmacogenet Genomics
Prif Awduron: Ramamoorthy, Anuradha, Flockhart, David A., Hosono, Naoya, Kubo, Michiaki, Nakamura, Yusuke, Skaar, Todd C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4411953/
https://ncbi.nlm.nih.gov/pubmed/20421845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e32833a1083
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