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Multiplex Amplicon Quantification (MAQ), a fast and efficient method for the simultaneous detection of copy number alterations in neuroblastoma

BACKGROUND: Cancer genomes display characteristic patterns of chromosomal imbalances, often with diagnostic and prognostic relevance. Therefore assays for genome-wide copy number screening and simultaneous detection of copy number alterations in specific chromosomal regions are of increasing importa...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kumps, Candy, Van Roy, Nadine, Heyrman, Lien, Goossens, Dirk, Del-Favero, Jurgen, Noguera, Rosa, Vandesompele, Jo, Speleman, Frank, De Preter, Katleen
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879279/
https://ncbi.nlm.nih.gov/pubmed/20459859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-298
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