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DREAM target reactivation by core transcriptional regulators supports neuroblastoma growth
Chromosome 17q gains are a common alteration in high-risk neuroblastomas with unknown functional significance. We identified a 17q super-enhancer regulated T-box Transcription Factor 2 (TBX2) as constituent of a core regulatory circuitry driving proliferation through enhancing V-myc myelocytomatosis...
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| Udgivet i: | Mol Cell Oncol |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6512935/ https://ncbi.nlm.nih.gov/pubmed/31131299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2019.1565470 |
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