Focal DNA Copy Number Changes in Neuroblastoma Target MYCN Regulated Genes

Neuroblastoma is an embryonic tumor arising from immature sympathetic nervous system cells. Recurrent genomic alterations include MYCN and ALK amplification as well as recurrent patterns of gains and losses of whole or large partial chromosome segments. A recent whole genome sequencing effort yielde...

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Detalhes bibliográficos
Main Authors: Kumps, Candy, Fieuw, Annelies, Mestdagh, Pieter, Menten, Björn, Lefever, Steve, Pattyn, Filip, De Brouwer, Sara, Sante, Tom, Schulte, Johannes Hubertus, Schramm, Alexander, Van Roy, Nadine, Van Maerken, Tom, Noguera, Rosa, Combaret, Valérie, Devalck, Christine, Westermann, Frank, Laureys, Geneviève, Eggert, Angelika, Vandesompele, Jo, De Preter, Katleen, Speleman, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537730/
https://ncbi.nlm.nih.gov/pubmed/23308108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052321
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