Focal DNA Copy Number Changes in Neuroblastoma Target MYCN Regulated Genes

Neuroblastoma is an embryonic tumor arising from immature sympathetic nervous system cells. Recurrent genomic alterations include MYCN and ALK amplification as well as recurrent patterns of gains and losses of whole or large partial chromosome segments. A recent whole genome sequencing effort yielde...

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Bibliografiska uppgifter
Huvudupphovsmän: Kumps, Candy, Fieuw, Annelies, Mestdagh, Pieter, Menten, Björn, Lefever, Steve, Pattyn, Filip, De Brouwer, Sara, Sante, Tom, Schulte, Johannes Hubertus, Schramm, Alexander, Van Roy, Nadine, Van Maerken, Tom, Noguera, Rosa, Combaret, Valérie, Devalck, Christine, Westermann, Frank, Laureys, Geneviève, Eggert, Angelika, Vandesompele, Jo, De Preter, Katleen, Speleman, Frank
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2013
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537730/
https://ncbi.nlm.nih.gov/pubmed/23308108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052321
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