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Genome surveillance in pluripotent stem cells: Low apoptosis threshold and efficient antioxidant defense
Pluripotent stem cells must be endowed with efficient genome surveillance. Here we describe the multiple mechanisms that ensure their genome integrity, including high susceptibility to apoptosis and efficient prevention of DNA lesions. In induced pluripotent stem cells, apoptosis hypersensitivity is...
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| Опубликовано в: : | Mol Cell Oncol |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Taylor & Francis
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4905369/ https://ncbi.nlm.nih.gov/pubmed/27308586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1052183 |
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