Genome surveillance in pluripotent stem cells: Low apoptosis threshold and efficient antioxidant defense

Pluripotent stem cells must be endowed with efficient genome surveillance. Here we describe the multiple mechanisms that ensure their genome integrity, including high susceptibility to apoptosis and efficient prevention of DNA lesions. In induced pluripotent stem cells, apoptosis hypersensitivity is...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Mol Cell Oncol
Päätekijät: Dannenmann, Benjamin, Lehle, Simon, Essmann, Frank, Schulze-Osthoff, Klaus
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis 2015
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905369/
https://ncbi.nlm.nih.gov/pubmed/27308586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1052183
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