Validation of Ultrasensitive Mutant Huntingtin Detection in Human Cerebrospinal Fluid by Single Molecule Counting Immunoassay

BACKGROUND: The measurement of disease-relevant biomarkers has become a major component of clinical trial design, but in the absence of rigorous clinical and analytical validation of detection methodology, interpretation of results may be misleading. In Huntington’s disease (HD), measurement of the...

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Bibliographic Details
Published in:J Huntingtons Dis
Main Authors: Fodale, Valentina, Boggio, Roberto, Daldin, Manuel, Cariulo, Cristina, Spiezia, Maria Carolina, Byrne, Lauren M., Leavitt, Blair R., Wild, Edward J., Macdonald, Douglas, Weiss, Andreas, Bresciani, Alberto
Format: Artigo
Language:Inglês
Published: IOS Press 2017
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Research Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5757651/
https://ncbi.nlm.nih.gov/pubmed/29125493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JHD-170269
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