Validation of Ultrasensitive Mutant Huntingtin Detection in Human Cerebrospinal Fluid by Single Molecule Counting Immunoassay

BACKGROUND: The measurement of disease-relevant biomarkers has become a major component of clinical trial design, but in the absence of rigorous clinical and analytical validation of detection methodology, interpretation of results may be misleading. In Huntington’s disease (HD), measurement of the...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:J Huntingtons Dis
Autores principales: Fodale, Valentina, Boggio, Roberto, Daldin, Manuel, Cariulo, Cristina, Spiezia, Maria Carolina, Byrne, Lauren M., Leavitt, Blair R., Wild, Edward J., Macdonald, Douglas, Weiss, Andreas, Bresciani, Alberto
Formato: Artigo
Lenguaje:Inglês
Publicado: IOS Press 2017
Materias:
Research Report
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5757651/
https://ncbi.nlm.nih.gov/pubmed/29125493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JHD-170269
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares