Nalaganje...

Analysis of mutant and total huntingtin expression in Huntington’s disease murine models

Huntington’s disease (HD) is a monogenetic neurodegenerative disorder that is caused by the expansion of a polyglutamine region within the huntingtin (HTT) protein, but there is still an incomplete understanding of the molecular mechanisms that drive pathology. Expression of the mutant form of HTT i...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Fodale, Valentina, Pintauro, Roberta, Daldin, Manuel, Altobelli, Roberta, Spiezia, Maria Carolina, Bisbocci, Monica, Macdonald, Douglas, Bresciani, Alberto
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7746729/
https://ncbi.nlm.nih.gov/pubmed/33335120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-78790-5
Oznake: Označite
Brez oznak, prvi označite!