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Analysis of mutant and total huntingtin expression in Huntington’s disease murine models
Huntington’s disease (HD) is a monogenetic neurodegenerative disorder that is caused by the expansion of a polyglutamine region within the huntingtin (HTT) protein, but there is still an incomplete understanding of the molecular mechanisms that drive pathology. Expression of the mutant form of HTT i...
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| Publicado en: | Sci Rep |
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| Autores principales: | , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7746729/ https://ncbi.nlm.nih.gov/pubmed/33335120 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-78790-5 |
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