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RIPK1 counteracts ZBP1-mediated necroptosis to inhibit inflammation
Receptor interacting protein kinase 1 (RIPK1) regulates cell death and inflammation via kinase-dependent and -independent functions1–7. RIPK1 kinase activity induces caspase-8-dependent apoptosis and RIPK3/Mixed Lineage Kinase Like (MLKL)-dependent necroptosis8–13. In addition, RIPK1 inhibits apopto...
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| 出版年: | Nature |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5755685/ https://ncbi.nlm.nih.gov/pubmed/27819681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature20558 |
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