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RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis
Necroptosis has emerged as an important pathway of programmed cell death in embryonic development, tissue homeostasis, immunity and inflammation(1–8). RIPK1 is implicated in inflammatory and cell death signalling(9–13) and its kinase activity is believed to drive RIPK3-mediated necroptosis(14,15). H...
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| Główni autorzy: | , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2014
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4206266/ https://ncbi.nlm.nih.gov/pubmed/25132550 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13608 |
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