RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis

Necroptosis has emerged as an important pathway of programmed cell death in embryonic development, tissue homeostasis, immunity and inflammation(1–8). RIPK1 is implicated in inflammatory and cell death signalling(9–13) and its kinase activity is believed to drive RIPK3-mediated necroptosis(14,15). H...

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Main Authors: Dannappel, Marius, Vlantis, Katerina, Kumari, Snehlata, Polykratis, Apostolos, Kim, Chun, Wachsmuth, Laurens, Eftychi, Christina, Lin, Juan, Corona, Teresa, Hermance, Nicole, Zelic, Matija, Kirsch, Petra, Basic, Marijana, Bleich, Andre, Kelliher, Michelle, Pasparakis, Manolis
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4206266/
https://ncbi.nlm.nih.gov/pubmed/25132550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13608
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