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Helix‐7 in Argonaute2 shapes the microRNA seed region for rapid target recognition

Argonaute proteins use microRNAs (miRNAs) to identify mRNAs targeted for post‐transcriptional repression. Biochemical assays have demonstrated that Argonaute functions by modulating the binding properties of its miRNA guide so that pairing to the seed region is exquisitely fast and accurate. However...

詳細記述

保存先:
書誌詳細
出版年:EMBO J
主要な著者: Klum, Shannon M, Chandradoss, Stanley D, Schirle, Nicole T, Joo, Chirlmin, MacRae, Ian J
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5753032/
https://ncbi.nlm.nih.gov/pubmed/28939659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201796474
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