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Helix‐7 in Argonaute2 shapes the microRNA seed region for rapid target recognition
Argonaute proteins use microRNAs (miRNAs) to identify mRNAs targeted for post‐transcriptional repression. Biochemical assays have demonstrated that Argonaute functions by modulating the binding properties of its miRNA guide so that pairing to the seed region is exquisitely fast and accurate. However...
Shranjeno v:
| izdano v: | EMBO J |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
John Wiley and Sons Inc.
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5753032/ https://ncbi.nlm.nih.gov/pubmed/28939659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201796474 |
| Oznake: |
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