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mRNA structural dynamics shape Argonaute-target interactions

small interfering RNAs (siRNAs) promote RNA degradation in a variety of processes and have important clinical applications. siRNAs direct cleavage of target RNAs by guiding Argonaute2 (AGO2) to its target site. Target site accessibility is critical for AGO2-target interactions, but how target site a...

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書目詳細資料
發表在:Nat Struct Mol Biol
Main Authors: Ruijtenberg, Suzan, Sonneveld, Stijn, Cui, Tao Ju, Logister, Ive, de Steenwinkel, Dion, Xiao, Yao, MacRae, Ian J., Joo, Chirlmin, Tanenbaum, Marvin E.
格式: Artigo
語言:Inglês
出版: 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8210632/
https://ncbi.nlm.nih.gov/pubmed/32661421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-020-0461-1
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