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The Crystal Structure of Human Argonaute2
Argonaute proteins form the functional core of the RNA-induced silencing complexes (RISCs) that mediate RNA silencing in eukaryotes. The 2.3 Å resolution crystal structure of human Argonaute2 (Ago2) reveals a bi-lobed molecule with a central cleft for binding guide and target RNAs. Nucleotides 2 to...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3521581/ https://ncbi.nlm.nih.gov/pubmed/22539551 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1221551 |
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