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Purification and Assembly of Human Argonaute, Dicer and TRBP complexes

The RNA-induced silencing complex (RISC) is a programmable gene-silencing machine involved in many aspects of eukaryotic biology. In humans, RISC is programmed or “loaded” with a small guide RNA by the action of a tri-molecular assembly termed the RISC-loading complex (RLC). The human RLC is compose...

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Detalhes bibliográficos
Main Authors: De, Nabanita, MacRae, Ian J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3532949/
https://ncbi.nlm.nih.gov/pubmed/21528450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-046-1_8
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