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Structure of the Human Dicer-TRBP Complex by Electron Microscopy

Dicer is a specialized ribonuclease that initiates RNA interference (RNAi) by cleaving double-stranded RNA (dsRNA) into small RNA fragments about 22 nucleotides in length. Here, we present the three dimensional structure of human Dicer bound to the protein TRBP at ~20 angstrom resolution determined...

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Detalhes bibliográficos
Main Authors: Lau, Pick-Wei, Potter, Clinton S., Carragher, Bridget, MacRae, Ian J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880462/
https://ncbi.nlm.nih.gov/pubmed/19836333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2009.08.013
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