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The Molecular Architecture of Human Dicer

Dicer is a multi-domain enzyme that generates small RNAs for gene silencing in eukaryotes. Current understanding of Dicer structure is restricted to simple forms of the enzyme, while that of the large and complex Dicer, widespread in eukarya, is unknown. Here, we describe a novel domain localization...

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Bibliographic Details
Main Authors: Lau, Pick-Wei, Guiley, Keelan Z., De, Nabanita, Potter, Clinton S., Carragher, Bridget, MacRae, Ian J.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319852/
https://ncbi.nlm.nih.gov/pubmed/22426548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2268
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