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A Dynamic Search Process Underlies MicroRNA Targeting
Argonaute proteins play a central role in mediating post-transcriptional gene regulation by microRNAs (miRNAs). Argonautes use the nucleotide sequences in miRNAs as guides for identifying target messenger RNAs for repression. Here we used single-molecule FRET to directly visualize how human Argonaut...
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| Publicado en: | Cell |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4768356/ https://ncbi.nlm.nih.gov/pubmed/26140593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.06.032 |
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