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Induction and Micro-CT Imaging of Cerebral Cavernous Malformations in Mouse Model
Mutations in the CCM1 (aka KRIT1), CCM2, or CCM3 (aka PDCD10) gene cause cerebral cavernous malformation (CCM) in humans. Mouse models of CCM disease have been established by tamoxifen induced deletion of Ccm genes in postnatal animals. These mouse models provide invaluable tools to investigate mole...
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| Udgivet i: | J Vis Exp |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MyJove Corporation
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5752174/ https://ncbi.nlm.nih.gov/pubmed/28892037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/56476 |
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