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eCD4-Ig promotes ADCC activity of sera from HIV-1-infected patients

Antibody-dependent cell-mediated cytotoxity (ADCC) can eliminate HIV-1 infected cells, and may help reduce the reservoir of latent virus in infected patients. Sera of HIV-1 positive individuals include a number of antibodies that recognize epitopes usually occluded on HIV-1 envelope glycoprotein (En...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Davis-Gardner, Meredith E., Gardner, Matthew R., Alfant, Barnett, Farzan, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5749896/
https://ncbi.nlm.nih.gov/pubmed/29253851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006786
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