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eCD4-Ig Variants That More Potently Neutralize HIV-1
The human immunodeficiency virus type 1 (HIV-1) entry inhibitor eCD4-Ig is a fusion of CD4-Ig and a coreceptor-mimetic peptide. eCD4-Ig is markedly more potent than CD4-Ig, with neutralization efficiencies approaching those of HIV-1 broadly neutralizing antibodies (bNAbs). However, unlike bNAbs, eCD...
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| Gepubliceerd in: | J Virol |
|---|---|
| Hoofdauteurs: | , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Microbiology
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5974481/ https://ncbi.nlm.nih.gov/pubmed/29593050 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02011-17 |
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