eCD4-Ig Limits HIV-1 Escape More Effectively than CD4-Ig or a Broadly Neutralizing Antibody

The engineered antibody-like entry inhibitor eCD4-Ig neutralizes every human immunodeficiency virus type 1 (HIV-1), HIV-2, and simian immunodeficiency virus isolate it has been tested against. The exceptional breadth of eCD4-Ig derives from its ability to closely and simultaneously emulate the HIV-1...

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Bibliografske podrobnosti
izdano v:J Virol
Main Authors: Fellinger, Christoph H., Gardner, Matthew R., Weber, Jesse A., Alfant, Barnett, Zhou, Amber S., Farzan, Michael
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2019
Teme:
Vaccines and Antiviral Agents
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6600210/
https://ncbi.nlm.nih.gov/pubmed/31068428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00443-19
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