Interleukin-1 blockade in acute decompensated heart failure: A randomized, double-blinded, placebo-controlled pilot study

BACKGROUND: Heart failure is an inflammatory disease. Patients with acute decompensated heart failure (ADHF) exhibit significant inflammatory activity upon admission. We hypothesized that Interleukin-1 (IL-1) blockade, with anakinra (Kineret™, Swedish Orphan Biovitrum), would quench the acute inflam...

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Bibliografske podrobnosti
izdano v:J Cardiovasc Pharmacol
Main Authors: Van Tassell, Benjamin W., Abouzaki, Nayef A., Erdle, Claudia Oddi, Carbone, Salvatore, Trankle, Cory, Melchior, Ryan D., Turlington, Jeremy S., Thurber, Clint, Christopher, Sanah, Dixon, Dave L., Fronk, Daniel Taylor, Thomas, Christopher S., Rose, Scott W., Buckley, Leo Francis, Dinarello, Charles A., Biondi-Zoccai, Giuseppe, Abbate, Antonio
Format: Artigo
Jezik:Inglês
Izdano: 2016
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5749643/
https://ncbi.nlm.nih.gov/pubmed/26906034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0000000000000378
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