Interleukin-1 Blockade in Recently Decompensated Systolic Heart Failure: Results from the REcently Decompensated Heart failure Anakinra Response Trial (REDHART)

BACKGROUND: An enhanced inflammatory response predicts worse outcomes in heart failure (HF). We hypothesized that administration of Interleukin-1 (IL-1) receptor antagonist (anakinra) could inhibit the inflammatory response and improve peak aerobic exercise capacity in patients with recently decompe...

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Pubblicato in:Circ Heart Fail
Autori principali: Van Tassell, Benjamin W., Canada, Justin, Carbone, Salvatore, Trankle, Cory, Buckley, Leo, Erdle, Claudia Oddi, Abouzaki, Nayef A., Dixon, Dave, Kadariya, Dinesh, Christopher, Sanah, Schatz, Aaron, Regan, Jessica, Viscusi, Michele, Buono, Marco Del, Melchior, Ryan, Mankad, Pranav, Lu, Juan, Sculthorpe, Robin, Biondi-Zoccai, Giuseppe, Lesnefsky, Edward, Arena, Ross, Abbate, Antonio
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5699505/
https://ncbi.nlm.nih.gov/pubmed/29141858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.117.004373
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