Interleukin-1 Blockade in Recently Decompensated Systolic Heart Failure: Results from the REcently Decompensated Heart failure Anakinra Response Trial (REDHART)

BACKGROUND: An enhanced inflammatory response predicts worse outcomes in heart failure (HF). We hypothesized that administration of Interleukin-1 (IL-1) receptor antagonist (anakinra) could inhibit the inflammatory response and improve peak aerobic exercise capacity in patients with recently decompe...

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Detalhes bibliográficos
Publicado no:Circ Heart Fail
Main Authors: Van Tassell, Benjamin W., Canada, Justin, Carbone, Salvatore, Trankle, Cory, Buckley, Leo, Erdle, Claudia Oddi, Abouzaki, Nayef A., Dixon, Dave, Kadariya, Dinesh, Christopher, Sanah, Schatz, Aaron, Regan, Jessica, Viscusi, Michele, Buono, Marco Del, Melchior, Ryan, Mankad, Pranav, Lu, Juan, Sculthorpe, Robin, Biondi-Zoccai, Giuseppe, Lesnefsky, Edward, Arena, Ross, Abbate, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5699505/
https://ncbi.nlm.nih.gov/pubmed/29141858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.117.004373
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