Study on the effect of EMD386088, a 5-HT(6) receptor partial agonist, in enhancing the anti-immobility action of some antidepressants in rats

The effect of some antidepressants co-administered with EMD386088 in the modified forced swim test in rats was investigated. Additionally, the pharmacokinetics, metabolic stability, and the effect of EMD386088 on P450 cytochromes were determined. Intraperitoneal (i.p.) coadministration of EMD386088...

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Detalhes bibliográficos
Publicado no:Naunyn Schmiedebergs Arch Pharmacol
Main Authors: Jastrzębska-Więsek, Magdalena, Siwek, Agata, Partyka, Anna, Kołaczkowski, Marcin, Walczak, Maria, Smolik, Magdalena, Latacz, Gniewomir, Kieć-Kononowicz, Katarzyna, Wesołowska, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2017
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5748433/
https://ncbi.nlm.nih.gov/pubmed/29079874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00210-017-1431-y
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