Study of a mechanism responsible for potential antidepressant activity of EMD 386088, a 5-HT(6) partial agonist in rats

It was shown that 5-HT(6) receptor agonists can exert pharmacological activity due to various modifications in monoamines’ level and metabolism activity in rats’ brain structures. This finding was correlated with antidepressant- or anxiolytic-like properties of these compounds. The study was designe...

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Dades bibliogràfiques
Publicat a:Naunyn Schmiedebergs Arch Pharmacol
Autors principals: Jastrzębska-Więsek, Magdalena, Siwek, Agata, Partyka, Anna, Antkiewicz-Michaluk, Lucyna, Michaluk, Jerzy, Romańska, Irena, Kołaczkowski, Marcin, Wesołowska, Anna
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2016
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4939156/
https://ncbi.nlm.nih.gov/pubmed/27106213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00210-016-1245-3
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