Metabolic and Cardiovascular Benefits and Risks of EMD386088—A 5-HT(6) Receptor Partial Agonist and Dopamine Transporter Inhibitor

Since 5-HT(6) receptors play role in controlling feeding and satiety and dopamine is essential for normal feeding behavior, we evaluated the ability of EMD 386088—5-HT(6) receptor partial agonist and dopamine transporter inhibitor—to reduce body weight in obese rats, as well as its anorectic propert...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Kotańska, Magdalena, Śniecikowska, Joanna, Jastrzębska-Więsek, Magdalena, Kołaczkowski, Marcin, Pytka, Karolina
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5296348/
https://ncbi.nlm.nih.gov/pubmed/28228713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2017.00050
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