Cellubrevin/vesicle-associated membrane protein-3–mediated endocytosis and trafficking regulate platelet functions

Endocytosis is key to fibrinogen (Fg) uptake, trafficking of integrins (αIIbβ(3), α(v)β(3)), and purinergic receptors (P2Y(1), P2Y(12)), and thus normal platelet function. However, the molecular machinery required and possible trafficking routes are still ill-defined. To further identify elements of...

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Vydáno v:Blood
Hlavní autoři: Banerjee, Meenakshi, Joshi, Smita, Zhang, Jinchao, Moncman, Carole L., Yadav, Shilpi, Bouchard, Beth A., Storrie, Brian, Whiteheart, Sidney W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2017
Témata:
Platelets and Thrombopoiesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746669/
https://ncbi.nlm.nih.gov/pubmed/28931526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-02-768176
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