Arf6 controls platelet spreading and clot retraction via integrin α(IIb)β(3) trafficking

Platelet and megakaryocyte endocytosis is important for loading certain granule cargo (ie, fibrinogen [Fg] and vascular endothelial growth factor); however, the mechanisms of platelet endocytosis and its functional acute effects are understudied. Adenosine 5'-diphosphate–ribosylation factor 6 (...

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Detalles Bibliográficos
Publicado en:Blood
Main Authors: Huang, Yunjie, Joshi, Smita, Xiang, Binggang, Kanaho, Yasunori, Li, Zhenyu, Bouchard, Beth A., Moncman, Carole L., Whiteheart, Sidney W.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2016
Assuntos:
Platelets and Thrombopoiesis
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4797022/
https://ncbi.nlm.nih.gov/pubmed/26738539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-05-648550
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