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Cellubrevin/vesicle-associated membrane protein-3–mediated endocytosis and trafficking regulate platelet functions

Endocytosis is key to fibrinogen (Fg) uptake, trafficking of integrins (αIIbβ(3), α(v)β(3)), and purinergic receptors (P2Y(1), P2Y(12)), and thus normal platelet function. However, the molecular machinery required and possible trafficking routes are still ill-defined. To further identify elements of...

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Détails bibliographiques
Publié dans:Blood
Auteurs principaux: Banerjee, Meenakshi, Joshi, Smita, Zhang, Jinchao, Moncman, Carole L., Yadav, Shilpi, Bouchard, Beth A., Storrie, Brian, Whiteheart, Sidney W.
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746669/
https://ncbi.nlm.nih.gov/pubmed/28931526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-02-768176
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