Cellubrevin/vesicle-associated membrane protein-3–mediated endocytosis and trafficking regulate platelet functions

Endocytosis is key to fibrinogen (Fg) uptake, trafficking of integrins (αIIbβ(3), α(v)β(3)), and purinergic receptors (P2Y(1), P2Y(12)), and thus normal platelet function. However, the molecular machinery required and possible trafficking routes are still ill-defined. To further identify elements of...

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Dettagli Bibliografici
Pubblicato in:Blood
Autori principali: Banerjee, Meenakshi, Joshi, Smita, Zhang, Jinchao, Moncman, Carole L., Yadav, Shilpi, Bouchard, Beth A., Storrie, Brian, Whiteheart, Sidney W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2017
Soggetti:
Platelets and Thrombopoiesis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746669/
https://ncbi.nlm.nih.gov/pubmed/28931526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-02-768176
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