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Alterations in platelet secretion differentially affect thrombosis and hemostasis

We genetically manipulated the major platelet vesicle-associated membrane proteins (VAMP2, VAMP3, and VAMP8) to create mice with varying degrees of disrupted platelet secretion. As previously shown, loss of VAMP8 reduced granule secretion, and this defect was exacerbated by further deletion of VAMP2...

詳細記述

保存先:
書誌詳細
出版年:Blood Adv
主要な著者: Joshi, Smita, Banerjee, Meenakshi, Zhang, Jinchao, Kesaraju, Akhil, Pokrovskaya, Irina D., Storrie, Brian, Whiteheart, Sidney W.
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Hematology 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6134224/
https://ncbi.nlm.nih.gov/pubmed/30185436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018019166
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