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Alterations in platelet secretion differentially affect thrombosis and hemostasis
We genetically manipulated the major platelet vesicle-associated membrane proteins (VAMP2, VAMP3, and VAMP8) to create mice with varying degrees of disrupted platelet secretion. As previously shown, loss of VAMP8 reduced granule secretion, and this defect was exacerbated by further deletion of VAMP2...
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| Publicado en: | Blood Adv |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society of Hematology
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6134224/ https://ncbi.nlm.nih.gov/pubmed/30185436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018019166 |
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