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Association with Aurora-A Controls N-MYC-Dependent Promoter Escape and Pause Release of RNA Polymerase II during the Cell Cycle

MYC proteins bind globally to active promoters and promote transcriptional elongation by RNA polymerase II (Pol II). To identify effector proteins that mediate this function, we performed mass spectrometry on N-MYC complexes in neuroblastoma cells. The analysis shows that N-MYC forms complexes with...

詳細記述

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書誌詳細
出版年:Cell Rep
主要な著者: Büchel, Gabriele, Carstensen, Anne, Mak, Ka-Yan, Roeschert, Isabelle, Leen, Eoin, Sumara, Olga, Hofstetter, Julia, Herold, Steffi, Kalb, Jacqueline, Baluapuri, Apoorva, Poon, Evon, Kwok, Colin, Chesler, Louis, Maric, Hans Michael, Rickman, David S., Wolf, Elmar, Bayliss, Richard, Walz, Susanne, Eilers, Martin
フォーマット: Artigo
言語:Inglês
出版事項: Cell Press 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746598/
https://ncbi.nlm.nih.gov/pubmed/29262328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.11.090
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