Association with Aurora-A Controls N-MYC-Dependent Promoter Escape and Pause Release of RNA Polymerase II during the Cell Cycle

MYC proteins bind globally to active promoters and promote transcriptional elongation by RNA polymerase II (Pol II). To identify effector proteins that mediate this function, we performed mass spectrometry on N-MYC complexes in neuroblastoma cells. The analysis shows that N-MYC forms complexes with...

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Publicado no:Cell Rep
Main Authors: Büchel, Gabriele, Carstensen, Anne, Mak, Ka-Yan, Roeschert, Isabelle, Leen, Eoin, Sumara, Olga, Hofstetter, Julia, Herold, Steffi, Kalb, Jacqueline, Baluapuri, Apoorva, Poon, Evon, Kwok, Colin, Chesler, Louis, Maric, Hans Michael, Rickman, David S., Wolf, Elmar, Bayliss, Richard, Walz, Susanne, Eilers, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746598/
https://ncbi.nlm.nih.gov/pubmed/29262328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.11.090
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